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The arca mentor school (ams)

The ARCA Mentor School (AMS) is a collaborative project involving the ARCA scientific Board, Intramed Communications and I-PRO.
The aim of AMS is to nurture a new generation of scientists able to exploit structured collections of real world data bridging the gap among biomedical sciences, data management, statistics and industrial exploitation. The format comprehends both residential training sessions and web-based follow up periods.

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4° EDITION, SIENA (ITALY), 18-19 September 2019

The fourth edition. From May 2019 registrations are open.​

3° EDITION, SIENA (ITALY), 20-21 September 2017

The third edition of the training course was held in Siena and it was attended by Italian young clinicians and virologists expecting to learn how to manage data for their scientific projects. 
The AMS is a collaborative project involving the ARCA scientific Board www.dbarca.net ,  Intramed Communications,  I-PRO and EURESIST Network GEIE. 
arca_programma_20-21sett.pdf
Video AMS2017

2° edition, siena (italy), 6-7 october 2016

The second ARCA Mentor School (AMS) was held in Siena, on 6-7 October 2016. This edition was devoted to the training of clinicians, virologists and experimenters on the possible uses of the ARCA database and observational databases in general. The School involved about 40 participants and 30 teachers/speakers. All participants were assigned to working groups, led by tutors for exercise sessions. Themes of the course were: the critical formulation of the hypothesis of the study, the methods for searching answers to clinical questions by targeted queries, the data analysis, the path of presentation and publication of the results.
As a further implementation of the format already successfully tested in 2015, the edition 2016 included the important issue of pharmacoeconomics, oriented to the analysis of costs projections as a key element of public planning on healthcare. To this
purpose, the governance of the School welcomed the experts of CREATE (Consortium for Applied Research in Economic Health). Download the programme  ||  Download the collaboration user manual

Sessions on 6 October - presentations and training materials:

1. Presentazione del corso - Prof. M. Zazzi - UOC Malattie Infettive, AOUS - Dipartimento Biotecnologie Mediche, UNISI - Siena
2. I dati di HIV ed epatiti nelle coorti italiane - Andrea De Luca - UOC Malattie Infettive, AOUS - Dipartimento Biotecnologie Mediche, UNISI Siena
3. Virological and immunological efficacy of regimen including MVC - Dott.ssa Barbara Rossetti UOC Malattie Infettive AOU Senese
4. Presentazione delle query: discussione e verifica congruità database ARCA per ciascuna query - Stefano Rusconi - Divisione Clinicizzata  di Malattie Infettive DIBIC “Luigi Sacco” Università degli Studi di Milano​
5. Group A - AMS 2016 - Virological failures to raltegravir (RAL) in ARCA database 
6. Group A - Drug resistance profile at failure of integrase inhibitors containing regimens - Dott.ssa Laura A. Nicolini  - Malattie Infettive-Genova 
7. Group B  - Frequenza di fallimento della terapia di prima linea basata su INI vs. PI a partire dal 2008 (anno di inizio INI), durability dei due tipi di trattamento e caratteristiche del paziente selezionato per DTG in prima linea (inclusa analisi di efficacia per follow-up possibile ad oggi)
8. Group C  - Caratteristiche dei pazienti che sono messi in trattamento con terapia a due farmaci DRV/r+3TC vs. ATV/r+3TC, analisi di efficacia e durability del trattamento
9. Group E -  Valutazione durability delle terapie HAART di prima linea dal 2010 al 2016
10. Query MVC
11. Group B AMS 2015 - Confronto tra la comparsa di mutazioni di resistenza al fallimento di regimi di prima linea contenenti 2 NRTI + DRV/rtv oppure ATV/rtv ​

Sessions on 7 October - presentations and training materials:

1. La condivisione dei dati - Francesca Incardona
2. Data integration - Roberto D’Autilia
3. I database locali: la nostra esperienza - Dott.ssa Simona Di Giambenedetto - Fondazione Policlinico «A.Gemelli»  Roma
4. Cosa abbiamo imparato dai database locali - HIV-RER - Vanni Borghi AOU - Modena
5. Group A - Virological failures to raltegravir (RAL) in ARCA database
6. Group B - Frequenza di fallimento della terapia di prima linea basata su INI vs. PI a partire dal 2008 (anno di inizio INI), durability dei due tipi di trattamento e caratteristiche del paziente selezionato per DTG in prima linea (inclusa analisi di efficacia per follow-up possibile ad oggi)
7. Group C - Caratteristiche dei pazienti che sono messi in trattamento con terapia a due farmaci DRV/r+3TC vs. ATV/r+3TC, analisi di efficacia e durability del trattamento
8. Group D - Risposta virologia nei cambi di terapia in pazienti coinfetti  con HCV con HIV-RNA non rilevabile nei quali si passa a una terapia che include RAL a partire da una terapia efficace che non include
9. Group E - Valutazione durability delle terapie HAART di prima linea dal 2010 al 2016 - Dott. Paolo Simoni

Go to the project ARCA.

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1° edition, siena (italy), 28-29 MAY 2015

​The first ARCA Mentor School (AMS) was held in Siena, on 28-29 May 2015. This edition was devoted to clinicians and investigators, training them in using the ARCA database and other similar DBs.  Participants learned how to enhance the data and how to write queries in order to get useful answers to the most relevant clinical questions related to chronic infections such as HIV, HBV and HCV.

​The course was registered on the site of AGENAS for CME accreditation. Download the programme