ABILITA2 || TROCAR || MeuSIX || KRG-DHIS || ARCA || AMS || ABILITA ||RARE || IKR || EuResist || SecurePhone
ARCA (Antiretroviral Resistance Cohort Analysis) is a public database for the studying of resistance to anti-HIV drugs (antiretroviral drugs). It is fed by data coming from different centres, mostly universities and care facilities.
The database is aimed to develop mathematical prediction models of response to anti-HIV treatment, providing a freely accessible tool to optimize therapies. More in particular:
• it is freely provided a hosting service for anonymous demographic information (year of birth, sex, first detection of HIV virus, country of origin, probable way of HIV acquisition), clinical information (AIDS-defining events, 27 HCV and HBV status, HLA typing), viroimmunological information (CD4 cells absolute and percentage level, test results of coreceptors tropism) and therapeutic information (antiretroviral treatments with start and end date and end reason) related to more than 18.000 patients followed in more than 100 clinical centres and laboratories involved in the project.
• for research use only, it is freely provided a phylogenetic analysis service along with resistance profile interpretation (AntiRetroScan software patented by University of Siena)
• it is possible to view basic statistical elaborations.
Since 2015 it is open the Arca Mentor School project (AMS), a collaborative initiative involving the ARCA scientific Board, Intramed Communications and I-PRO.
Information and materials on AMS 2015 and 2016 are available here.
The official site of the ARCA project is www.dbarca.net
Antiretroviral Resistance Cohort Analysis
Università di Siena
INMI L. Spallanzani, Roma
Università di Milano
Università Cattolica del Sacro Cuore, Roma
Università Vita-Salute San Raffaele, Milano
Università di Tor Vergata, Roma
Università di Padova
Università di Roma Tre
Università di Brescia
II Università di Napoli
Università di Foggia
Ospedale Niguarda Milano
Università di Pavia